WASHINGTON—Labor regulations implemented during the Obama administration could cost an estimated $81 billion over the next 10 years and require more than 400 million hours in paperwork, according to a new study from the National Association of Manufacturers’ Center for Manufacturing Research.

WASHINGTON—A new report finds that U.S. manufacturers are subject to 2,183 different federal regulations promulgated since 1981, and those regulations will decrease the nation’s GDP by as much as $630 billion this year.